Instantly

Every Medication Every Interaction

Unlock Your DNA
for Better Health

Works with or without a genetic test
PGxIQ® is a comprehensive AI-powered pharmacovigilance platform. It screens your medications for drug-drug, drug-food, drug-lifestyle, and drug-gene risks across all FDA-approved medications.
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FDA Approved Drugs
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Lifestyle & dietary factors
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Global clinical authorities
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Blind stress test score
PGxIQ logo
to start
Plus $40/yr · Pro $99/yr
Free tier covers 5 medications. No credit card required.

The Blind Spot: Interaction Checkers Catch Drug-Drug.

None Screen Drug-Gene.

Every major pharmacy system in North America screens for drug-drug interactions. But native screening for drug-gene interactions is also essential, as this is where some of the most dangerous adverse reactions can hide.
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The scope of the risk
Drugs carrying pharmacogenomic guidance account for 39% of adverse drug reactions and 53% of ADR-related hospitalizations.
FDA FAERS analysis
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Never genetically tested
The vast majority of patients have never had pharmacogenomic testing, so their genetic drug risks are invisible to every system they touch.
MyEngene market analysis
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Drug-gene interactions per patient
University of Alberta research found an average of 4.0 drug-gene interactions per patient, most going completely undetected.
Dr. Dalia Hamdy, J. Adv. Pharm. Sciences, Jan 2026

Complete Coverage

Four Interaction Types. One Screen.

PGxIQ is the only platform that checks all four risk categories at once, including the genetic layer no standard checker sees.
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Drug-Gene
1,100+ genes

Screens against CPIC, DPWG, FDA, EMA & Health Canada guidance, with or without your own genetic data.

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Drug-Drug

4,700+ medications
Every FDA-approved medication cross-checked for pairwise and cumulative polypharmacy risk.
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Drug-Food

Everyday triggers
Grapefruit, leafy greens, alcohol, caffeine, common foods that quietly change how your medications work.

Drug-Lifestyle

6,000+ factors
From supplements to sleep, exercise to smoking, evidence-based lifestyle interactions most tools ignore.
Five global authorities cross-referenced on every screen:
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How PGxIQ Works

Import

Enter your medication list, upload it, or pull it directly from your pharmacy or health record via API.

Analyze

4,600+ clinical parameters are cross-referenced against five global clinical authorities in seconds.

Act

Receive a ranked clinical report: each risk with its severity, mechanism, supporting source, and alternatives to discuss.

Works with any medication list, prescriptions, OTC drugs, and supplements.

Every candidate finding must be traced to an authoritative source, or it's suppressed, not reported.

You and your prescriber always control the final decision. PGxIQ informs, it never replaces.

Three steps • Quick results

No credit card required

Powered by Unmatched Intelligence

One of the World's Largest PGx Precision Medicine Databases

Continuously updated through automated integration with leading pharmacogenomic databases, FDA alerts, and clinical guidelines, daily.
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Genetic variants with clinical annotations
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Unique diplotypes
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Drug-gene pairs
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Lifestyle-drug interactions
Daily
FDA alert & guideline updates

Why You Can Trust It

AI That Never Guesses
PGxIQ is built on a deterministic multi-agent architecture, not a general-purpose chatbot. Same input, same output, every time. Every recommendation traceable to its source.
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Zero Fabrications
On a blind adversarial 13-medication polypharmacy case, PGxIQ produced 117 correct results out of 117. A 230B-parameter AI scored 80/117, with two clinically dangerous errors.
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Verification Tests - 100% Pass
FourWay architecture and formula verification testing across the entire pipeline, with a 100% pass rate.
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Patent Claims Mapped to Code
Every protected architectural claim is mapped directly to production code, confirming the deployed system matches the patented design.

Real-World Impact

Risks Hiding in Plain Sight

Scenarios like these pass through standard interaction checkers every day, with no alerts.
Case Study
"Breast cancer patient on an SSRI"
A patient takes tamoxifen for breast cancer and sertraline for anxiety. Everything looks routine, no alerts in the pharmacy system.
PGxIQ flags a major interaction immediately

Sertraline may reduce tamoxifen’s effectiveness by limiting its activation in the body. It recommends an alternative antidepressant and coordinating with the prescriber before therapy is compromised.

Case Study
"This antidepressant isn't working"
A patient keeps returning, saying their SSRI does nothing. They’re a CYP2D6 poor metabolizer, the drug never reaches therapeutic levels.
PGxIQ identifies the metabolizer status
It flags alternatives the patient can actually process, ending months of trial-and-error.

Pricing

Start Free

Upgrade When You Need More
iOS, Android & web
Free
$0
7 days trial
Everything you need to start
Plus
$40
/year
For you and your family
Pro
$99
/year
Maximum insight & sharing
30-day free trial
Starter
$249
/month
Solo pharmacist or clinic
Professional
$549
/month
Multi-pharmacist practice
Enterprise
1,099
/month
Per location – hospital systems

PGxIQ Overview

The same drug at the same dose can heal one person and harm another.

Your DNA may determines how you respond to medication. MyEngene® analyzes your DNA to identify which medications will work, which won’t, and which could cause harm before the first dose. Watch how PGxIQ makes every prescription safer.

Common Questions

Frequently Asked Questions

No. PGxIQ works instantly from your medication list, no genetic test required. It analyzes interactions across all 4,700+ FDA-approved drugs the moment you enter your medications. If you later take the PGxME genetic test, PGxIQ integrates those results automatically for genetically-enhanced alerts. Many users start with PGxIQ free and add PGxME when they want genetic depth.

Standard pharmacy systems screen drug-drug interactions only. PGxIQ screens all four interaction types simultaneously, drug-drug, drug-food, drug-lifestyle, and drug-gene, cross-referenced against five global clinical authorities (CPIC, DPWG, FDA, EMA, Health Canada). The drug-gene layer is where the most dangerous adverse reactions hide, and no standard checker screens it natively.

That’s exactly why PGxIQ isn’t built like a chatbot. It runs on a deterministic architecture: the same input always produces the same output, and every finding must be traced to an authoritative clinical source before it reaches your report, anything unverifiable is suppressed, not reported. In a blind stress test, PGxIQ scored 117/117 with zero fabricated outputs, while a leading 230B-parameter AI scored 80/117 with two clinically dangerous errors.

Yes. MyEngene is HIPAA, GDPR, PIPEDA, and CCPA compliant. Your data is encrypted with bank-level security (AES-256 at rest, TLS 1.3 in transit) and is never sold or shared with pharmaceutical companies, insurers, or anyone else without your explicit consent. You can delete your account and all associated data at any time, deletion is permanent within 30 days.
No, and it’s not meant to. PGxIQ is clinical decision support: it surfaces risks, explains the mechanism, cites the source, and suggests alternatives where established guidelines support one. You and your healthcare provider always control the final decision. Never change a prescription without consulting your doctor, PGxIQ’s job is to make that conversation better informed.
PGxIQ logo
Because knowing your medication risks shouldn’t take weeks.
Free to start. No genetic test. No credit card.